|Georgemr||Дата: Вт, 26.08.2014, 17:53 | Сообщение # 1|
|Patients treated with both dosing regimens of ixekizumab had significantly greater levels of film allowance compared to placebo and to etanercept at the 12-week endpoint. Skin leeway was unhurried close standard primary endpoints for psoriasis studies: the Psoriasis Parade-ground and Inhumanity Directory (PASI) and the Atmospherics Physician Epidemic Assessment (sPGA). |
Representing patients treated with ixekizumab either every four weeks or every two weeks, between 78 to 90 percent of patients achieved at least a 75 percent reduction in PASI score (PASI 75) at 12 weeks. Additionally, 31 to 41 percent of these patients achieved PASI 100, or unmistakable skin, at week 12. Destined for likeness, between 5 to 7 percent of patients treated with etanercept in the UNCOVER-2 and 3 studies achieved PASI 100.
Statistically valued improvements in pellicle room measures exchange for patients treated with ixekizumab were observed as early as the first week when compared to either placebo or etanercept, and continued owing to week 12. In the UNCOVER-1 ruminate on, cheerful levels of retort were maintained into done with 60 weeks of treatment.
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